Medical Director, ATTM-CM
Company: Intellia Therapeutics
Location: Cambridge
Posted on: March 25, 2026
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Job Description:
Why Join Intellia? Our mission is to develop curative genome
editing treatments that can positively transform the lives of
people living with severe and life-threatening diseases. Beyond our
science, we live our four core values: One, Explore, Disrupt,
Deliver and feel strongly that you can achieve more at Intellia. We
have a single-minded determination to excel and succeed together.
We believe in the power of curiosity and pushing boundaries. We
welcome challenging thoughts and imagination to develop innovative
solutions. And we know that patients are counting on us to make the
promise a reality, so we must maintain high standards and get it
done. We wantall ofour people to go beyond what is possible. We
aren’t constrained by typical end rails, and we aren’t out to just
“treat” people. We’re all in this for something more. We’re driven
to cure and motivated for change. Just imagine the possibilities of
what we can do together. How You Will Achieve More: The Medical
Lead will serve as a medical monitor for Intellia’s nex-z ATTR-CM
Phase 3 clinical trial. You will be an integral member of the
cross-functional clinical development strategy subteam (CDST) for
Intellia's nex-z ATTR-CM program and provide medical input to the
subteam efforts. As part of this role, you will support medical
monitoring work for Intellia’s Phase 3 CM clinical trial, a complex
cardiovascular outcome study in patients with progressive cardiac
and neurological disease with significant comorbid conditions. In
addition, as a physician, you will serve as a resource for medical
input across a range of programs including research.
Responsibilities: Partner with members of the CDST, as needed, to
develop global plans that define the path for each potential
medicine to approval and use in appropriate populations and
indications. Serve as the medical expert for the study team and
medical monitor for phase 1-4 clinical trials, as applicable. Given
complexity of the disease, its progressive nature in patients with
significant comorbid conditions, an MD is required. Assist in the
development of medical plans and decisions for assigned Intellia
clinical development programs. Partner with members of the
cross-functional team to develop clinical development plans that
define the path for each program to approval and registration in
applicable populations and indications. Key member of clinical
sub-team to execute these plans. Develop and maintain relationships
with academic investigators, pharmaceutical partners, KOL’s, and
patient advocacy groups. Provide medical information on existing
and emerging data. In response to questions from internal and
external stakeholders, and you will partner with pharmacovigilance
to best understand the safety profile of compounds. Contribute to
activities in support of the company’s regulatory submissions,
including authoring clinical sections for INDs, BLAs, and other
related documents. Author manuscripts and collaborate with
cross-functional colleagues and thought leaders to meet publication
plan objectives. Advise the pre-clinical project teams as
development candidates are brought forward to interpret
pre-clinical data, identify biomarkers, define a target product
profile, and plan for early phase trials. Participate in or lead
clinical discussions and due diligence with potential business
development partners in academia and industry. Supervisory
Responsibilities Recruits, interviews, hires, and trains clinical
scientists or director level roles. Provides constructive and
timely performance evaluations. Handles discipline and termination
of employees in accordance with company policy. About You: Served
as medical lead for drugs in development; multiple phases preferred
Experience in all aspects of trial conduct
(planning/start-up/execution/close out, reporting) Understanding of
global regulatory processes Participated in key regulatory
interactions with the FDA, EMA or similar national agencies;
BLA/NDA experience strongly preferred. Knowledge and experience in
gene editing/therapy is strongly preferred Knowledge, training and
experience in cardiology is preferred Understanding of drug
development process Top level clinical and scientific expertise in
relevant disease area Professional demeanor & excellent
interpersonal skills when dealing with external customers /
internal colleagues Ability to manage multiple tasks and deal
effectively with deadlines Creativity, resourcefulness, high energy
and flexibility Excellent verbal and written communication skills
MD At least 5 years in industry, with the majority in key clinical
development role LI-Onsite EEOC Statement: Intellia believes in a
diverse environment, and is committed to equal employment
opportunity for all its employees and qualified applicants. We do
not discriminate in recruitment, hiring, training, promotion or any
other employment practices for reasons of race, color, religion,
gender, national origin, age, sexual orientation, marital or
veteran status, disability, or any other legally protected status.
Intellia will make reasonable accommodations for qualified
individuals with known disabilities, in accordance with applicable
law. Applications are accepted on a rolling basis, and will
continue to be accepted until the position is filled at which point
the position will be taken down. The base salary for this position
is expected to range between $274,207.00 - $335,141.00 USD per
year. The salary offered is determined based on a range of factors
including, but not limited to, relevant education and training,
overall related experience, specialized, rare or in-demand skill
sets, internal comparators and other business needs. Upon joining
Intellia, your salary will be reviewed periodically and additional
factors such as time in role and performance will be considered.
Intellia may change the published salary range based on company and
market factors. Additional compensation includes a
performance-based annual cash bonus, a new hire equity grant, and
eligibility to be considered for annual equity awards the value of
which are determined annually at the Company’s discretion. For more
information about Intellia’s benefits, please click here .
Keywords: Intellia Therapeutics, Medford , Medical Director, ATTM-CM, Healthcare , Cambridge, Massachusetts
