Associate Scientist / Scientist - Process Development

Company: Greenlight Biosciences
Location: Medford
Posted on: March 28, 2020

Job Description:

Associate Scientist / Scientist - Process Development

Position Summary:

GreenLight Biosciences is seeking an exceptional and motivated scientist to help advance the company's RNA platform technology. The successful candidate will support R&D efforts within the company by developing scalable downstream processes for GreenLight's RNA products. Strong experience in chromatography, biochemistry, and molecular biology are required. Organizational and communication skills, creative problem-solving, and flexibility are essential.

Responsibilities:

-- Design and execute studies to develop scalable purification methods for RNA molecules, evaluating and optimizing steps such as chromatography, extraction, and filtration.

-- Characterize RNA products using state-of-the-art techniques, including capillary electrophoresis, immunoblotting, plate-based assays including ELISA, etc.

-- Collaborate with the analytical chemistry and pathway engineering groups on process design.

-- Support routine RNA sample production for internal and external programs.

-- Clearly communicate results and recommendations to colleagues and managers, assisting in project decision-making.

-- Contribute to the company's intellectual property portfolio by generating new ideas, reading broadly in relevant fields, and diligently maintaining organized records.

Qualifications:

--M.S. or Ph. D. in Chemical or Biological Engineering, Biochemistry, Molecular Biology, or related discipline with at least 3 years of relevant academic or industry experience. Leveling will depend on experience.

-- Experience purifying and characterizing macromolecules (proteins and/or nucleic acids) is required.

-- Experience with liquid chromatography systems (AKTA FPLC) is required.

-- Molecular biology experience, includingin vitro transcription, gel electrophoresis, capillary electrophoresis, and immunoblotting is preferred.

-- Experience with absolute and tangential flow filtration is desirable.

-- Knowledge of cell culture clarification methods is desirable.

-- Experience with enzymatic assays is desirable.

--Strong organization, communication, and interpersonal skills are required, with the ability to work both independently and in a collaborative work environment.

Keywords: Greenlight Biosciences, Medford , Associate Scientist / Scientist - Process Development, Other , Medford, Massachusetts