Scientist, Cell Biology
Company: Ensem Therapeutics
Posted on: May 9, 2022
ABOUT ENSEM THERAPEUTICS :
ENSEM Therapeutics ("ENSEM") is a Boston-based, preclinical stage
biopharmaceutical company focused on high value and
difficult-to-drug targets in oncology to address unmet medical
needs. The name ENSEM symbolizes innovations via the integration of
groundbreaking technologies to decipher structural ENSEMbles and
kinetics for drug design. The company's mission is to discover,
develop, and commercialize transformative oncology therapies for
patients, while leading the advancement of AI-driven structural
ensemble and computational drug design.
NOTE: This position will move from Medford to Waltham in
ENSEM Therapeutics is seeking experienced and motivated PhD-level
scientists with expertise in cancer cell biology to join our Cell
Biology team. In this role, you will design and perform cell
studies to evaluate small molecules for their ability to inhibit
oncogenic pathways. You will also assess novel drug targets for
their prioritization and integration into our discovery
Key Responsibilities :
Report to the Head of Biology or one of our senior biologists.
Design mechanistic assays for small molecule optimization and
manage external resources for routine compound testing.---
Characterize lead compounds and development candidates to help
advance projects to preclinical development and to enable
development of biomarkers and assays for use in first-in-human
Actively participate in discussions at project meetings and other
forums within the company, to leverage the opportunities to broaden
scientific and strategic insights.
Collaborate with colleagues from other functional areas to build
and maintain alignment on project goals and issues.--- Scientists
who demonstrate the requisite leadership skills will have future
opportunity to lead project teams and manage internal
All other duties as assigned
A PhD in Biology, Pharmacology, Cell or Molecular Biology with
experience in signal transduction pathways or gene expression
regulation in mammalian cells is required.--- Post-doctoral
training is required, except in the case of Associate
Proficiency in the characterization of proteins and nucleic acids,
using techniques such as immunoprecipitation, ELISA, RT-PCR, and
qPCR is required.--- Candidates should have extensive experience
with mammalian cell culture and transfection techniques, as well as
the design of expression plasmids.
Flexibility, adaptability, and multi-tasking in an
interdisciplinary, hybrid (internal/outsourcing) and multi-site
Exceptional interpersonal and communication skills to articulate
deliverables, progresses, and issues to the drug discovery team and
solicit feedbacks from team members and industrial and academic
Personal attributes: attention to details while focused on the big
picture; ability to scientifically influence and motivate others; a
team player who listens effectively and values feedbacks;
collaborative, open-minded, data-driven, and creative; persistent,
optimistic with can-do spirit.
ENSEM Therapeutics is an Equal Opportunity employer and does not
discriminate against an applicant or employee because of race,
creed, color, religion, sex, national origin, ancestry, age, sexual
orientation, physical or mental disability, or veteran status.
The duties listed in this job description are intended only as
illustrations of the various types of work that may be performed.
The omission of specific statements of duties does not exclude them
from the position if the work is similar, related, or a logical
assignment to the position.
Keywords: Ensem Therapeutics, Medford , Scientist, Cell Biology, Other , Medford, Massachusetts
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