Scientist/Sr. Scientist, Product Design and Development,

Company: Takeda Pharmaceutical
Location: Medford
Posted on: May 11, 2022

Job Description:

By clicking the "Apply" button, I understand that my employment application process with Takeda will commence and that the information I provide in my application will be processed in line with Takeda's and . I further attest that all information I submit in my employment application is true to the best of my knowledge.Job DescriptionAre you looking for a patient-focused, innovation-driven company that will inspire you and empower you to shine? Join us as a Scientist / Senior Scientist, Oncology Cell Therapy Innovation in our Cambridge, MA office.At Takeda, we are transforming the pharmaceutical industry through our R&D-driven market leadership and being a values-led company. To do this, we empower our people to realize their potential through life-changing work. Certified as a Global Top Employer, we offer stimulating careers, encourage innovation, and strive for excellence in everything we do. We foster an inclusive, collaborative workplace, in which our global teams are united by an unwavering commitment to deliver Better Health and a Brighter Future to people around the world.Here, you will be a vital contributor to our inspiring, bold mission.As a Scientist/Senior Scientist, Oncology Cell Therapy Innovation you will be empowered to join a world-class cell therapy team.POSITION OBJECTIVES:

• This position is looking for talent who has a solid background in immunology/cell biology/molecular biology, especially immune-oncology and innate immunology.
• This position will play an important role in optimizing cell therapy platforms to improve the biological function of cell therapy products and developing process and/or analytical methods for developing cellular therapy products, e.g. TCR-T, CAR-NK, CAR-gdT products (primary or iPSC derived)
• Independently plan and implement experiments to drive the development of cell therapy discovery platforms and target selection.
• Prepares study protocols, reports, technology transfer documentation, and regulatory documents for various studies.
• Responsible for participating and interacting on matrix project teams, presenting study results at team or department meetings, to external partners or at conferences.POSITION ACCOUNTABILITIES:
  • Understands project timelines and deliverables and plans/coordinates project work accordingly with departmental, functional and external stakeholders
  • Provides technical leadership to project teams within their area of expertise and commits resources to execute specific project tasks.
  • Contributes significantly and independently to project work which may include multiple projects within a functional area.
  • Supports TCR-T, NK and gdT cell therapy product development
  • Designs and conducts in vitro and in vivo experiments for evaluating allogeneic Immunol product
  • Reviews, interprets and communicates data cross-functionally within CMC and/or project teams.
  • Plans and implements resolutions to technical problems/issues
  • Represents functional area on project teams by communicating activities from designated functional area to project team
  • Independently designs and executes experiments, and reports results
  • Assists with the development of project strategy and communicates complex data/decisions within the department and cross-functionally as necessary
  • Builds and maintains relationships with key vendors and assists with technical aspects of vendor negotiations
  • Responsible for integrating scientific/technical efforts around cross-functional issues.EDUCATION, EXPERIENCE, BEHAVIOURAL COMPETENCIES, AND SKILLS:Education and Experience:Required:
    • Ph.D. in immunology, cancer biology, stem cell biology, biomedical engineering, chemical engineering, or related pharmaceutical science; 0-5+ years relevant industry/academic experience
    • Experience in working in a multi-disciplinary team environment
    • Demonstrated mastery of subject or area related to the fieldLINE FUNCTION-SPECIFIC QUALIFICATIONS:
      • Experience in developing cell therapy products (TCR-T, CAR-NK or iPSC derived cells), or experience in developing and executing cellular characterization assays, including flow cytometry-based, cell function (killing/cytokine) and molecular-based assay (qPCR, RNAseq etc)
      • Expert in T cell/NK cell/gdT cells and/or innate cell biology.
      • In-depth experience in principles and practices of cell biology methodologies, cellular immunology or stem cell biology (e.g., induced pluripotent stem cells (iPSCs)), including cell culture, immune cell activation/expansion, viral transduction (retroviral or lentiviral), development and execution of functional in vitro and in vivo methods relevant for various types of immune cells or stem cells.
      • In-depth knowledge of immune cell metabolism and in vitro assays is required to study cell metabolismKNOWLEDGE AND SKILLS:
        • Analytical and Problem-Solving Skills - Able to troubleshoot critical issues or problems, and determine causes and possible solutions
        • Teamwork -- Ability to work well in a highly cross-functional team environment and across global line functions.
        • Communication Skills -Able to express one's self clearly and concisely within the team; documents issues and/or concerns concisely with colleagues; adjusts communication style as appropriate for the audience; timely and effectively communicates issues to supervisor; technical writing skills to support the authorship of internal technical documents
        • Organization - Exercises good time management and prioritization skills and is able to successfully manage multiple tasks simultaneously
        • Knowledge Sharing - Ability to capture organizational knowledge; improve solutions, processes, and deliverables through use of information; improve information capital by contributing experience, theories, deliverables, and models for others to use
        • Resource Management -Ability to manage one's time within the individual, departmental, and corporate goals and timelines; management of internal and external resources (vendors)
        • External Involvement - Demonstrated involvement in professional community evidenced by presentation of scientific posters or lectures at professional conferences or events
        • Technical - Subject matter expertise and knowledge of applicable lab equipment and operations.TRAVEL REQUIREMENTS
          • May require approximately up to 0-5% travel -Updated Takeda U.S. Vaccine Requirement:Absent an approved religious or medical reason, all US office-based and lab-based Takeda employees who work fully on-site or in a hybrid model (as determined by Takeda) must be fully vaccinated to work at a Takeda site or to engage with Takeda colleagues or anyone else on behalf of Takeda. As of the same date, absent an approved religious or medical reason, US field-based employees, employees must be fully vaccinated in order to continue in their current roles. - US employees who work at a Takeda manufacturing facility, and those who work at a BioLife center or BioLife lab, may be subject to different guidelines. Candidates are encouraged to speak with their recruiter to seek further information on the applicable guidelines for the Business Unit/Function for which they have applied. -In accordance with the CO Equal Pay Act, Colorado Applicants Are Not Permitted to Apply. -WHAT TAKEDA CAN OFFER YOU:
            • 401(k) with company match and Annual Retirement Contribution Plan
            • Tuition reimbursement
            • -Company match of charitable contributions
            • Health & Wellness programs including onsite flu shots and health screenings
            • Generous time off for vacation and the option to purchase additional vacation days
            • Community Outreach ProgramsEmpowering Our People to ShineDiscover more at takedajobs.comNo Phone Calls or Recruiters Please.#LI-AA1EEO StatementTakeda is proud in its commitment to creating a diverse workforce and providing equal employment opportunities to all employees and applicants for employment without regard to race, color, religion, sex, sexual orientation, gender identity, gender expression, parental status, national origin, age, disability, citizenship status, genetic information or characteristics, marital status, status as a Vietnam era veteran, special disabled veteran, or other protected veteran in accordance with applicable federal, state and local laws, and any other characteristic protected by law.EEO StatementTakeda is proud in its commitment to creating a diverse workforce and providing equal employment opportunities to all employees and applicants for employment without regard to race, color, religion, sex, sexual orientation, gender identity, gender expression, parental status, national origin, age, disability, citizenship status, genetic information or characteristics, marital status, status as a Vietnam era veteran, special disabled veteran, or other protected veteran in accordance with applicable federal, state and local laws, and any other characteristic protected by law.LocationsBoston, MAWorker TypeEmployeeWorker Sub-TypeRegularTime TypeFull time

Keywords: Takeda Pharmaceutical, Medford , Scientist/Sr. Scientist, Product Design and Development,, Other , Medford, Massachusetts